Baltic Dry Index. 1675 -25 Brent Crude 66.13
Spot Gold 1734
Bitcoin Slides in Worst Weekly Drop Since March Amid Selloff
By Eric Lam and Olivia RaimondeUpdated on 26 February 2021, 22:14 GMT
· Selling in Grayscale trust may be contributing: Ayyar
The digital token slumped 20% this week, the most since the pandemic-fueled selloff last March. The wider Bloomberg Galaxy Crypto Index, tracking Bitcoin, Ether and three other cryptocurrencies, was down 23% for the same period.
Bitcoin fell 5% to trade at $45,672 as of 5:00 p.m. in New York, according to consolidated pricing compiled by Bloomberg.
“It is a market that was ridiculously overbought and will probably be so once again in the not-too-distant future,” Craig Erlam, a senior market analyst at OANDA Europe, said in a note Friday.
Wall Street Week Ahead: Investors weigh new stock leadership as broader market wobbles
HOUSTON (Reuters) - Troubled Texas power grid operator ERCOT on Friday said $2 billion in charges for power and services went unpaid, according to an official notice, signaling the financial fallout from high electricity rates is spreading to utilities.
It will cover $800 million of the shortfall by borrowing from internal accounts, and will draw an undisclosed amount from grid users with credit balances. A spokeswoman was unavailable for immediate comment.
Texas electric firm Griddy loses access to Texas grid, customers turned over to rivals
February 27, 2021
HOUSTON, Feb 26 (Reuters) - Texas’s power grid operator on Friday canceled Griddy Energy LLC’s access to the state’s power network, and shifted all its customers to other utilities, according to a notice by the grid operator.
Electric Reliability Council of Texas (ERCOT) said it had transferred Griddy’s customers to one or more rival providers. Griddy was the power marketer that sold consumers power at wholesale rates, which rose to $9,000 per megawatt hour for days as cold weather struck the state last week. (Reporting by Gary McWilliams, Editing by Rosalba O’Brien)
Texas’ ag industry faces hundreds of millions in losses after deep freeze
Weather has returned to normal in Texas — it was even sunny and 75 most of the week. But the state is still dealing with some interruptions in commerce from the Presidents’ Day freeze.
Grocery stores are getting restocked and many are almost back to normal, although some are still limiting the quantities of milk and eggs that people can buy. The freeze hit the agriculture industry hard. Preliminary estimates put the cost to Texas farmers and ranchers at hundreds of millions of dollars.
“We’re going to have a lot of farmers go bankrupt from this freeze,” said Sid Miller, Texas’ agriculture commissioner. He said farmers are on tight margins even without natural disasters and did what they could to prepare for the storms.
“You know, the tractors got antifreeze and block heaters,” Miller said. “We’ve got generators to run the dairy barn, but everybody else wasn’t ready. The milk processors went down, you know, the trucking companies and egg processors went down.”
Miller said dairy farmers had to dump 14 million gallons of milk because they couldn’t get it to processing plants.
A lot of poultry farmers lost power for days and couldn’t get more fuel for their generators.
“The baby chicks that just hatched that are, you know, going to be on your store shelves in three months, a lot of them froze to death,” Miller said.
He said Texas might have to import from other places if there’s a shortage which would make milk, chicken and eggs more expensive at the grocery store. Stores can’t just immediately restock shelves because they don’t keep a lot of extra stock on hand.
More
Exclusive: China's Huawei, reeling from U.S. sanctions, plans foray into EVs – sources
February 26, 20216:06 AM
HONG KONG/BEIJING (Reuters) - China’s Huawei plans to make electric vehicles under its own brand and could launch some models this year, four sources said, as the world’s largest telecommunications equipment maker, battered by U.S. sanctions, explores a strategic shift.
Huawei plans to start making cars - sources
Huawei Technologies Co Ltd is in talks with state-owned Changan Automobile and other automakers to use their car plants to make its electric vehicles (EVs), according to two of the people familiar with the matter.
Huawei is also in discussions with Beijing-backed BAIC Group’s BluePark New Energy Technology to manufacture its EVs, said one of the two and a separate person with direct knowledge of the matter.
The plan heralds a potentially major shift in direction for Huawei after nearly two-years of U.S. sanctions that have cut its access to key supply chains, forcing it to sell a part of its smartphone business to keep the brand alive.
Huawei was placed on a trade blacklist by the Trump administration over national security concerns. Many industry executives see little chance that blocks on the sale of billions of dollars of U.S. technology and chips to the Chinese company, which has denied wrongdoing, will be reversed by his successor.
A Huawei spokesman denied the company plans to design EVs or produce Huawei branded vehicles.
“Huawei is not a car manufacturer. However through ICT (information and communications technology), we aim to be a digital car-oriented and new-added components provider, enabling car OEMs (original equipment manufacturers) to build better vehicles.”
Huawei has started internally designing the EVs and approaching suppliers at home, with the aim of officially launching the project as early as this year, three of the sources said.
Richard Yu, head of Huawei’s consumer business group who led the company to become one of the world’s largest smartphone makers, will shift his focus to EVs, said one source. The EVs will target a mass-market segment, another source said.
I’ve been rich and I’ve been poor. Rich is better.
Frank Sinatra.
Covid-19 Corner
This section will continue until it becomes unneeded.
J&J’s One-Shot Covid Vaccine Receives FDA Advisers’ Backing
By Robert Langreth and Riley Griffin· Clearance could come soon after panel’s vote to recommend
Johnson & Johnson’s single-shot coronavirus vaccine won the backing of a panel of U.S. government advisers, paving the way for authorization of the country’s third immunization against the deadly virus.
Experts advising the U.S. Food and Drug Administration voted 22-0, with no abstentions, that the benefits of the vaccine outweigh its risks in adults 18 and older, a decision that could help bolster the vaccine supply as new variants continue to spread. The FDA usually follows the nonbinding recommendations of its advisory panels and could authorize the shot within days.
The J&J candidate is highly anticipated because it can be kept in a refrigerator for three months, an advantage over the mRNA vaccines that must be frozen when stored for longer periods, and its single-shot regime. Biden administration officials have said the U.S. expects J&J to release 3 million to 4 million shots next week, assuming it’s authorized for use.
“This is a relatively easy call,” said Eric Rubin, a committee member who’s also editor-in-chief of the New England Journal of Medicine. “It clearly gets us way over the bar, and it’s nice to have a single-dose vaccine.”
Israeli researchers say spirulina algae could reduce COVID mortality rate
The algae has been shown to reduce inflammation.
By MAAYAN JAFFE-HOFFMAN FEBRUARY 24, 2021 21:17
A team of scientists from Israel and Iceland have published research showing that an extract of spirulina algae has the potential to reduce the chances of COVID-19 patients developing a serious case of the disease.
The research, published in the peer-reviewed journal Marine Biotechnology, found that an extract of photosynthetically manipulated Spirulina is 70% effective in inhibiting the release of the cytokine TNF-a, a small signaling protein used by the immune system.
The research was conducted in a MIGAL laboratory in northern Israel with algae grown and cultivated by the Israeli company VAXA, which is located in Iceland. VAXA received funding from the European Union to explore and develop natural treatments for coronavirus.
Iceland’s MATIS Research Institute also participated in the study.
In a small percentage of patients, infection with the coronavirus causes the immune system to release an excessive number of TNF-a cytokines, resulting in what is known as a cytokine storm. The storm causes acute respiratory distress syndrome and damage to other organs, the leading cause of death in COVID-19 patients.
“If you control or are able to mitigate the excessive release of TNF-a, you can eventually reduce mortality,” said Asaf Tzachor, a researcher from the IDC Herzliya School of Sustainability and the lead author of the study.
During cultivation, growth conditions were adjusted to control the algae’s metabolomic profile and bioactive molecules. The result is what Tzachor refers to as “enhanced” algae.
Tzachor said that despite the special growth mechanism, the algae are a completely natural substance and should not produce any side effects. Spirulina is approved by the US Food and Drug Administration as a dietary substance. It is administrated orally in liquid drops.
“This is natural, so it is unlikely that we would see an adverse or harmful response in patients as you sometimes see in patients that are treated with chemical or synthetic drugs,” he said.
The algae have been shown to reduce inflammation. Tzachor said that if proven effective, spirulina could also be used against other coronaviruses and influenza.
More
UK team testing tablet, spray alternatives to COVID-19 vaccine
February 24, 2021 18:49
LONDON: Researchers who produced the Oxford University COVID-19 vaccine are assessing the use of tablets or nasal sprays to replace jabs.
Lead researcher Sarah Gilbert told a parliamentary committee that “we’re … thinking about second-generation formulations of vaccines” that could replace injections, but they will “take time to develop.”
She added: “We have flu vaccines that are given by nasal spray, and this could be a very good approach in the future to use vaccines against coronaviruses.
“It’s also possible to consider oral vaccination where you have to take a tablet that will give the immunization, and that would have a lot of benefits for vaccine rollout — if you didn’t need to use the needles and syringes for people.”
Both options “will have to be tested for safety and then for efficacy as well, because the immune responses that will be generated by both of those approaches will be a little bit different to what we get from an intramuscular injection,” Gilbert said.
Kate Bingham, who chaired the UK government’s vaccines taskforce, said two injections given by healthcare professionals is “not a good way of delivering vaccines.”
She told the BBC: “We need to get vaccine formats which are much more scalable and distributable, so whether they’re pills or patches or nose sprays.”
https://www.arabnews.com/node/1815236/world
Nasal Sprays Are Part Of The Fight Against Covid-19. Here's How
Several sprays in development are showing promising results for preventing – and even treating – infection.
By Natasha Hinde 26/02/2021 06:00am GMT
If Covid-19 vaccines are the superheroes, fighting against the worst effects of coronavirus with a needle and vial, they’re soon set to get a seriously kick-ass sidekick in different guise: the nasal spray.
Teams of scientists around the world are hard at work developing sprays that will not only deliver Covid-19 vaccines into the body – great news for needle phobics – but may also help prevent and treat early infection from the virus.
The nose, you see, is a key entry point for the SARs-CoV-2 virus. It gets in via the droplets produced when someone infected with Covid-19 coughs, sneezes or speaks. Cells inside the nose have more of a certain receptor – the ACE-2 receptor – than other cells in the body, and these are like magnets for the coronavirus, making the nose far more susceptible to the unwanted invader.
There, the virus can lock on to and enter cells using its spike protein – and rapidly multiply. This is why it’s so important to wear a face mask over your nose as well as mouth – but it’s also where nasal spray vaccines come in...
----One such spray, called Taffix, has already been found to prevent Covid-19 from occurring. A trial among Orthodox Jews attending a religious festival in Israel in September 2020 found that while the celebration was effectively a super-spreader event – with infections in the local population rising from 18% to 28% – a small group of people didn’t seem to be impacted much.
The reason? They used a nasal spray. Of 243 participants, 83 used the Taffix spray during the two-day event and for the following two weeks. The spray is thought to work in 50 seconds and offers protection for up to five hours.
When rates of infection were examined, two participants in the nasal spray group tested positive for Covid-19 compared to 16 in the group who declined the product. This equated to a 78% reduction in risk of infection when the spray was used.
The spray wouldn’t be a replacement for face masks, warn its creators – rather an additional layer of protection. Dr Dalia Meggido, co-founder and chief executive officer of Nasus Pharma, the biopharma company that developed the spray, said it could be particularly useful in high-risk settings such as on public transport and in shops and schools.
----A nasal antiviral created by researchers at Columbia University was found to block transmission of SARS-CoV-2 in ferrets and researchers are hopeful the same results could be achieved in humans. The compound in the Columbia University spray – a lipopeptide developed by researchers – is designed to prevent the new coronavirus from entering host cells in the nose.
Scientists at Lancaster University began working on a nasal spray in March 2020 that aims not only to prevent infection but stop the virus spreading. They ran animal trials on hamsters from July to September, and are currently analysing the results with a team of researchers at the Biomedical Research Institute in San Antonio, Texas before human trials can begin.
----Australian biotech company, Ena Respiratory, has also been working on a nasal spray that aims to help prevent Covid-19 – by boosting the immune system. It works by stimulating the innate immune system, the first line of defence against the invasion of pathogens into the body.
When taken once or twice weekly, this nasal spray reduced viral replication of SARS-CoV-2 by up to 96% in ferrets. By boosting the immune response at the primary site of infection, the ability of the Covid-19 virus to infect and replicate was dramatically reduced, a study by Public Health England showed.
While nasal sprays are proving to be useful in preventing the virus from entering the body’s cells, some are being developed which could also act as treatments for early infection. One Canadian nasal spray is being tested as a treatment for the virus in clinical trials at Ashford and St Peter’s Hospitals NHS Foundation Trust in Surrey. The nitric oxide nasal spray – called SaNOtize – is designed to kill the SARS-CoV-2 virus in the upper airways and stop it from replicating and spreading to the lungs.
In lab tests, the spray proved to be 99.9% effective in killing the virus within two minutes, and in animal tests, rodents who were given the spray and deliberately infected with the virus saw a 95% drop in viral load within a day of infection, while others showed no detectable virus.
More
https://www.huffingtonpost.co.uk/entry/nasal-spray-covid_uk_60366c9dc5b62daa0bffac88
Professor Tim Spector. Approx. 6 minutes.
Reasons to be cheerful as COVID cases stall
https://www.youtube.com/watch?v=ZULTz5EWKbw
Next, some very useful vaccine links kindly sent along from a LIR reader in Canada. The links come from a most informative update from Stanford Hospital in California.
World Health Organization - Landscape of COVID-19 candidate vaccines. https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines
NY Times Coronavirus Vaccine Tracker. https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html
Stanford Website. https://racetoacure.stanford.edu/clinical-trials/132
FDA information. https://www.fda.gov/media/139638/download
Regulatory Focus COVID-19 vaccine tracker. https://www.raps.org/news-and-articles/news-articles/2020/3/covid-19-vaccine-tracker
Some more useful Covid links.
Johns Hopkins Coronavirus resource centre
https://coronavirus.jhu.edu/map.html
Rt Covid-19
The Spectator Covid-19 data tracker (UK)
https://data.spectator.co.uk/city/national
Technology Update.
With events happening fast in the development of solar power and graphene, I’ve added this section. Updates as they get reported. Is converting sunlight to usable cheap AC or DC energy mankind’s future from the 21st century onwards.
Fire risk prompts ban on electrics in underground car parks
(dpa) - Electric cars may be less of a burden on the environment than diesels, but a serious downside to these zero-emission vehicles is the fire risk they pose in underground car parks.
The issue has prompted officials in Germany to ban electrics from underground car parks in two towns after a blaze broke out in a subterranean lot.
The car that burned out two months ago in Kulmbach in Bavaria was elderly petrol-engined VW Golf hatchback and not a pure electric. However, the damage caused was extensive and the facility had to be shut down for five months.
Officials said the consequences would have been much worse if a battery car had caught fire. Now Teslas, all other electrics and even petrol and diesel hybrids are no longer allowed to use two underground car parks in Kulmbach and Leonberg in the German state of Baden-Wuerttemberg.
In other countries, a wider debate on whether electrics should be banned from underground car parks and tunnels was sparked after a Swiss researchers published footage of the loud bang, metre-long flames and copious amounts of thick, black smoke caused by an electric car on fire.
To see what the impact of burning electric car batteries would be on rescue services and other nearby drivers in tunnels or car parks, the Swiss Materials Testing and Research Institute (Empa) deliberately set a number of electric cars on fire in enclosed spaces.
The resulting video footage and findings, published in September 2020, are somewhat alarming.
"The visibility in the previously brightly lit tunnel section quickly approaches zero," the testers said, backing up their analysis with various videos of exploding electric cars. "After a few minutes, the battery module is completely burnt out."
Their conclusion from tests: Fire departments familiar with fires in conventional cars should be prepared to deal with this kind of fire, and the tunnel or underground car park walls and pipes should not be put at additional risk.
Experts in Germany said their fire brigades cannot extinguish electric car fires easily since the lithium-ion batteries on board continue to smoulder even when doused with water. In some cases the fire can break out again.
The only way to deal with an underground car park car fire is to let the vehicle burn out since the roof of the car park is usually too low to allow heavy equipment to drag out a blazing vehicle.
Another complex method of extinguishing electrics which catch fire is to submerge them completely a container of water. This prevents re-ignition and the emission of toxic gases.
Although electric cars do not burst into flames more often than those with combustion engines, the blazes are usually serious.
In some cases rescuers are unable to free passengers from a burning vehicle because of the extremely high temperatures generated by burning batteries. A further hazard are short circuits of up to 1,000 volts in the car's high-voltage circuits.
After dozens of initially unexplained fires, South Korean maker Hyundai recently recalled thousands of three all-electric models on sale in the domestic market and replaced their batteries. The maker acted after a report highlighted the batteries as the cause of the blazes.
This weekend’s musical diversion. Approx. 7 minutes.
Domènec Terradellas (1713-1751) - Sinfonia 'Sesostri, re d'Egitto' (1751)
https://www.youtube.com/watch?v=DI1zmpVLJbw
Domènec Terradellas
Domènec Terradellas (baptized 13 February 1713, Barcelona – 20 May 1751, Rome) was a Catalan opera composer. The birthdate is sometimes incorrectly given as 1711.[a] Carreras i Bulbena did extensive research in contemporary documents, such as baptismal records, and found that the correct date was 1713. All his works are thoroughly Italian in style.
----- Terradellas was one of a group of foreign-born composers who studied in Italy and adopted the Italian style. The reason for this is that Italian opera was by far the dominant genre of opera at this time, attracting composers from all across Europe: (George Frideric Handel, Johann Adolph Hasse, Johann Christian Bach (all Germans), Thomas Arne (an Englishman), Josef Mysliveček (a Czech), and Vicente Martín y Soler (a Spaniard).
More
https://en.wikipedia.org/wiki/Dom%C3%A8nec_Terradellas
This weekend something for the air history followers. Approx. 10 minutes.
Germany's U-2 - WW2s Highest Air Combat
https://www.youtube.com/watch?v=8WDkj0ZYuiA&t=525s
Finally, everything you ever wanted to know about late WW2 super-prop fighters and why the lost out to jet aircraft. Great detail. Approx. 26 minutes.
U.S. "Super Prop" Fighters P-51H, XP-72, and more
https://www.youtube.com/watch?v=fgIz5N11TZ8
Bob Hope -Chester Hooton: Am I dead?
Bing Crosby-Duke Johnson: I can't tell, you always look that way.
The Road to Utopia, 1946.